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OF the 50 million Americans living and coping with autoimmune disease (AD), more than 75 percent of them are women. ( I just found this on www.aarda.org)  


Autoimmune disorders are ubiquitous and prevalent amongst Americans who have grown up in the age of the discovery of antibiotics with the discovery of penicillin by Alexander Fleming in 1928.  Since that time, we have had a plethora of discoveries and breakthroughs in the space of medicine and vaccination.  Unfortunately we did not know then what we know now about the delicate microbiome of the intestines and how the intake of antibiotics disturbs the balance of flora and bacteria in the gut.  We are learning; however, that when we kill the bacteria causing an infection we are also killing off the microbiome balance and then it becomes difficult to measure and restore.  


Possibly in the future, science will have evolved to the point when someone is taking an antibiotic (for the first time on an untouched intestine) then the gut will be measured beforehand and then after to see the effects on the microflora.





It is now shown that an estimated 23.5 million Americans suffer with an autoimmune condition and 50 million Americans are currently suffering and have been suffering in pain and been undiagnosed.  (Why the difference? The NIH numbers only include 24 diseases for which good epidemiology studies were available.)

Autoimmune and leaky gut are connected

Autoimmune Disease…is a major health problem.


Researchers have identified 80-100 different autoimmune diseases and suspect at least 40 additional diseases of having an autoimmune basis. These diseases are chronic and can be life-threatening.


Autoimmune disease is one of the top 10 leading causes of death in female children and women in all age groups up to 64 years of age.


A close genetic relationship exists among autoimmune disease, explaining clustering in individuals and families as well as a common pathway of disease.


Commonly used immunosuppressant treatments lead to devastating long-term side effects.


The Institute of Medicine reports that the US is behind other countries in research into immune system self recognition, the process involved in autoimmune disease.


Understanding how to modulate immune system activity will benefit transplant recipients, cancer patients, AIDS patients and infectious disease patients.


As you can see above (* I don't think they can see above)?   that researchers have identified 80-100 distinct autoimmune diseases thus far, one of the most prevalent conditions of hypothyroidism is called Hashimoto's dosease. More recently, some groups estimate that 27 million Americans have thyroid disease, and about 13 million of them are undiagnosed.




We are looking at the effects of eating a ketogenic diet on the thyroid, specifically through both research and self-experimentation and testing. There is a link between thyroid disorders and autoimmune conditions.  Specifically, it was found that the majority of people with thyroid disease in the U.S. have an underlying autoimmune thyroid disease that is causing their condition. And autoimmune diseases are definitely on the rise. (Reference). So it makes sense that with more autoimmunity, there will be an increase in thyroid disease as a result.




Some testing that can be helpful to have as a marker to show you how your thyroid is functioning and if you are producing normal levels of the hormones are the following: 


TSH test
T4 tests
T3 test
thyroid-stimulating immunoglobulin (TSI) test
antithyroid antibody test, also called the thyroid peroxidase antibody test (TPOab)


When the thyroid gland isn't working properly there is a correlation to weight gain or weight loss.  A correlation between a low basal metabolic rate and an underactive thyroid is what is commonly called Hypothyroidism.  When the thyroid produces too much hormone, the body uses energy faster than it should. This condition, overactive thyroid, is called Hyperthyroidism.  What happens to the thyroid to throw it out of balance?  Why does this occur?  And why does it occur more commonly in women then in men?  (Hashimotos disease affects women ten times more than men). 

Thyroid gland hormones can affect food metabolism, mood, and sexual function. There are a small minority of women who have Hypothyroidism and do not experience weight gain, but this is not the vast majority, who do experience weight gain.  The difference in these types of women is their individual biochemistry, how each indivudal uses their calories. Many many women in particular have thyroid levels that are out of balance and are on thyroid medications, a common one called Synthroid.  If instead of treating the symtom you are someone who is eager to get underneath the cause of the issue, Keto Upgrade is a method toward healing your thyroid levels by changing your metabolism and returning thyroid levels back to normal.  For example, when Kerri, who is not overweight and has never been, but has been diagnosed with an autoimmune disease had tested for TSH T3 T4 TSI and more in the begininning of her journey toward Keto adaption, her numbers were:


Three months later, when she was in full Ketogensis and she re-tested her thyroid function, this was revealed.  

Her tests show: 


A metobolic burn, the rate at which you metabolize food, can still fall instead of increase when dieting if your thyroid levels are low.  In order to fix your metabolism, you need to understand your entire body's function, not just the thyroid, but it is very hepful to understand this organ and the way it functions by produing hormones.




The thyroid in women


More women than men suffer from hypothyroidism, and many more women than men with thyroid issues have problems with weight gain. Most thyroid problems occur within the gland itself and often don’t reveal themselves until a broader pattern of hormonal imbalance develops. That’s why thyroid issues, menopause and weight gain often appear together.


Why do women experience low thyroid and weight gain with such frequency?  The reasons are manifold, but primarily:


  • Women spend much of their lives dieting, usually in a yo-yo cycle of feasting and then fasting. This undermines your metabolism and decreases your metabolic rate, a compounding factor for the thyroid, especially duringperimenopause.

  • Women tend to internalize stress, which affects their adrenal, brain, and thyroid function, resulting in increased cravings for sweets and simple carbs to provide instant energy and feel good hormones.

  • Women experience monthly hormonal fluctuations that affect their biochemistry.

The thyroid and weight gain  Cited from https://www.womentowomen.com/thyroid-health/hypothyroidism-thyroid-issues-and-weight-gain/